drugstr
Central, NJ
Male, 61
I have worked as a drug discovery scientist for over 30 years performing experiments to help identify novel chemical compounds for their potential in treating diseases in the areas of infection, inflammation and cardiovascular disorders. I have a good familiarity with the entire process from discovery to safety to clinical trials and even marketing. Ask me about the business of Big Pharma. I’m happy to comment on any and all hot-button issues. My opinions are quite often not pro-business.
Sorry for the late response. I hope you're doing well and enjoying the program. I think that your training would prepare you well for your goal. I have seen Pharm. D.s working at all levels, but I must say that research leadership tends to be composed mainly of PhDs and MDs. Still, your success will depend entirely on your skills and ambition. Good luck!
Share Answer: 
This is not a pharma question and I’m not expert in colligative properties, however, my understanding is that freezing point depression is a function of the molality of a solute in a solution. The molality represents the total number of dissolved particles. You’re obviously familiar with this since your list includes compounds of increasing molal potential. I submit that based on molality, aluminum chloride would be best so long as the solution was fairly dilute. While the others nicely dissolve in water, AlCl3 reacts with water and forms HCl, a dissolved gas. In a concentrated solution some of the HCl would degas and thus lower the molality reducing the freezing point depression. So if your goal is a several degree drop, choose CaCl2. It’s a safer bet.
Share Answer: 
I would say that if these physicians' claims of success in treating COVID-19 patients are accurate then their methods should, indeed, be adopted by others. Having said that, their belief that hydroxychloroquine and azithromycin are the keys to positive outcomes is dubious. There's more to patient care than drugs. Bona fide, well-controlled clinical studies have shown these two to be of no benefit. I'm a little on the fence, however, about zinc. Zinc has a number of roles in biology. The one I'm thinking of is its interaction with protein which can influence tertiary structure (shape) and in so doing interfere with virus binding. As you probably know, zinc is purported to be a remedy for the common cold. Who knows? Maybe there's something there.
Share Answer: 
No I haven't. I never worked with patients nor am I aware of any one dying from an adverse event while on a drug that I was involved in developing.
Share Answer: 
Stand-Up Comedian
How do you fend off hecklers?
Small Website Owner
What made you go the entrepreneur route after college instead of a typical job?
Bodybuilder
How prevalent is steroid use in pro bodybuilding?
These two drugs are not chemically related. Both have sedation as a side effect of their modes of action. Trazadone is an antidepressant. Etorphine is a powerful synthetic opiate significantly more potent than fentanyl. It's considered too dangerous to be used in human medicine. In veterinary medicine its use often requires reversal with an antidote. Thus, it's not practical as a treatment for insomnia.
Share Answer: 
This is not a pharma question.No numbers have been changed. Evidently, a CDC report on comorbidities was the source of this misinformation.
Share Answer: 
According to the FDA there is no effective HCQ regimen for the treatment of COVID-19. Its emergency use is no longer authorized. I refer you to the link below for answers to your three questions.https://www.fda.gov/drugs/drug-safety-and-availability/fda-cautions-against-use-hydroxychloroquine-or-chloroquine-covid-19-outside-hospital-setting-or
Share Answer: 
-OR-
Login with Facebook (max 20 characters - letters, numbers, and underscores only. Note that your username is private, and you have the option to choose an alias when asking questions or hosting a Q&A.)
(A valid e-mail address is required. Your e-mail will not be shared with anyone.)
(min 5 characters)
By checking this box, you acknowledge that you have read and agree to Jobstr.com’s Terms and Privacy Policy.
-OR-
Register with Facebook(Don't worry: you'll be able to choose an alias when asking questions or hosting a Q&A.)
Browse Jobs
Host a Q&A
Search
Submit Your Question
Host a Q&A
Last 7
